Ecuador has agreed to allow US military planes to operate from an airport on the Galapagos Islands, reports say.
US aircraft will be able to use San Cristobal airport, Ecuador's defence minister Oswaldo Jarrin has been quoted as saying.
They will "fight drug trafficking" under a deal with Ecuador's government, Mr Jarrin said.
The reported deal has prompted concerns over the potential impact on the environment and Ecuador's sovereignty.
The aircraft involved include a Boeing 777 and a Lockheed P-3 Orion, Latin American TV network Telesur reports.
The Galapagos Islands, 563 miles (906km) west of continental Ecuador, are a Unesco World Heritage site renowned worldwide for their unique array of plants and wildlife.